{"product_id":"rapgef1-antibody-abccs64573","title":"RAPGEF1 Antibody","description":"\u003ch4\u003eSize\u003c\/h4\u003e\u003cp\u003e100ul\u003c\/p\u003e\u003ch4\u003eClone Number\u003c\/h4\u003e\u003cp\u003e\u003c\/p\u003e\u003ch4\u003eAliases\u003c\/h4\u003e\u003cp\u003eC3G antibody; C3G protein antibody; CRK SH3 binding GNRP antibody; CRK SH3-binding GNRP antibody; DKFZp781P1719 antibody; GRF 2 antibody; GRF2 antibody; Guanine nucleotide releasing factor 2 (specific for crk proto oncogene) antibody; Guanine nucleotide releasing factor 2 antibody; Guanine nucleotide-releasing factor 2 antibody; OTTHUMP00000064558 antibody; Protein C3G antibody; Rap guanine nucleotide exchange factor (GEF) 1 antibody; Rap guanine nucleotide exchange factor 1 antibody; RAPGEF 1 antibody; RAPGEF1 antibody; RPGF1_HUMAN antibody\u003c\/p\u003e\u003ch4\u003eImmunogen Species\u003c\/h4\u003e\u003cp\u003eHomo sapiens (Human)\u003c\/p\u003e\u003ch4\u003eUniProt ID\u003c\/h4\u003e\u003cp\u003eQ13905\u003c\/p\u003e\u003ch4\u003eImmunogen\u003c\/h4\u003e\u003cp\u003ePeptide sequence from Human Rap guanine nucleotide exchange factor 1 protein (22-40AA)\u003c\/p\u003e\u003ch4\u003eRaised in\u003c\/h4\u003e\u003cp\u003eRabbit\u003c\/p\u003e\u003ch4\u003eSpecies Reactivity\u003c\/h4\u003e\u003cp\u003eHuman\u003c\/p\u003e\u003ch4\u003eTested Applications\u003c\/h4\u003e\u003cp\u003eELISA, WB; Recommended dilution: WB:1:1000-1:5000\u003c\/p\u003e\u003ch4\u003eBackground\u003c\/h4\u003e\u003cp\u003eGuanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2\/ASH. Transduces signals from CRK to activate RAS. Plays a role in the establishment of basal endothelial barrier function. Plays a role in nerve growth factor (NGF)-induced sustained activation of Rap1 and neurite outgrowth.\u003c\/p\u003e\u003ch4\u003eClonality\u003c\/h4\u003e\u003cp\u003ePolyclonal\u003c\/p\u003e\u003ch4\u003eIsotype\u003c\/h4\u003e\u003cp\u003eIgG\u003c\/p\u003e\u003ch4\u003ePurification Method\u003c\/h4\u003e\u003cp\u003e\u0026gt;95%, Protein G purified\u003c\/p\u003e\u003ch4\u003eConjugate\u003c\/h4\u003e\u003cp\u003eNon-conjugated\u003c\/p\u003e\u003ch4\u003eBuffer\u003c\/h4\u003e\u003cp\u003ePreservative: 0.03% Proclin 300\u003cbr\u003eConstituents: 50% Glycerol, 0.01M PBS, pH 7.4\u003c\/p\u003e\u003ch4\u003eForm\u003c\/h4\u003e\u003cp\u003eLiquid\u003c\/p\u003e\u003ch4\u003eStroage\u003c\/h4\u003e\u003cp\u003eUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003ch4\u003eTarget Names\u003c\/h4\u003e\u003cp\u003eRAPGEF1\u003c\/p\u003e\u003ch4\u003eResearch Areas\u003c\/h4\u003e\u003cp\u003eSignal transduction\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"Default Title","offer_id":42255245410538,"sku":"ABCCS64573","price":299.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_dfe7c3d5-9f2d-486b-b651-8130c2b5f074.png?v=1650624668","url":"https:\/\/danabiosci.com\/products\/rapgef1-antibody-abccs64573","provider":"Dana Bioscience","version":"1.0","type":"link"}