{"product_id":"raf-b-phospho-thr599-polyclonal-antibody-abcb07073","title":"Raf-B(Phospho Thr599) Polyclonal Antibody","description":"\u003ch4\u003eAb type\u003c\/h4\u003e\u003cp\u003ePrimary antibody\u003c\/p\u003e\u003ch4\u003eBackground\u003c\/h4\u003e\u003cp\u003eThis gene encodes a protein belonging to the raf\/mil family of serine\/threonine protein kinases. This protein plays a role in regulating the MAP kinase\/ERKs signaling pathway| which affects cell division| differentiation| and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome| a disease characterized by heart defects| mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers| including non-Hodgkin lymphoma| colorectal cancer| malignant melanoma| thyroid carcinoma| non-small cell lung carcinoma| and adenocarcinoma of lung. A pseudogene| which is located on chromosome X| has been identified for this gene. \u003c\/p\u003e\u003ch4\u003eReactivity\u003c\/h4\u003e\u003cp\u003eHuman, Mouse, Rat\u003c\/p\u003e\u003ch4\u003eClonality\u003c\/h4\u003e\u003cp\u003ePolyclonal\u003c\/p\u003e\u003ch4\u003eHost\u003c\/h4\u003e\u003cp\u003eRabbit\u003c\/p\u003e\u003ch4\u003eIsotype\u003c\/h4\u003e\u003cp\u003eIgG\u003c\/p\u003e\u003ch4\u003eImmunogen\u003c\/h4\u003e\u003cp\u003eThe antiserum was produced against synthesized peptide derived from human B-RAF around the phosphorylation site of Thr599. AA range:571-620\u003c\/p\u003e\u003ch4\u003eStorage Stability\u003c\/h4\u003e\u003cp\u003e-20°C for 1 year\u003c\/p\u003e\u003ch4\u003eConcentration\u003c\/h4\u003e\u003cp\u003e1 mg\/ml\u003c\/p\u003e\u003ch4\u003eMolecularWeight_Da\u003c\/h4\u003e\u003cp\u003e84437\u003c\/p\u003e\u003ch4\u003esynonyms\u003c\/h4\u003e\u003cp\u003eSerine\/threonine-protein kinase B-raf; BRAF; BRAF1; RAFB1; Serine\/threonine-protein kinase B-raf; Proto-oncogene B-Raf; p94; v-Raf murine sarcoma viral oncogene homolog B1\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":42404509516010,"sku":"ABCB07073","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_6b93130c-3a28-4726-bb30-853694d3d78b.png?v=1645222872","url":"https:\/\/danabiosci.com\/products\/raf-b-phospho-thr599-polyclonal-antibody-abcb07073","provider":"Dana Bioscience","version":"1.0","type":"link"}