{"product_id":"r36477-100ug","title":"CNGB3 Antibody","description":"\u003cp\u003eVisual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. Cyclic nucleotide-gated cation channel beta-3 can be activated by cGMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficiency of the channel when coexpressed with CNGA3 (By similarity). Essential for the generation of light-evoked electrical responses in the red-, green- and blue sensitive cones. [UniProt]\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug \/ Goat","offer_id":49476172054808,"sku":"R36477-100UG","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_1b0bddc5-1b27-4607-9d20-f46f1e6acec5.jpg?v=1734468947","url":"https:\/\/danabiosci.com\/products\/r36477-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}