{"product_id":"r32443","title":"TAK1 Antibody \/ MAP3K7","description":"\u003cp\u003eMitogen-activated protein kinase kinase kinase 7, also known as TAK1, is an enzyme that in humans is encoded by the MAP3K7 gene. The protein encoded by this gene is a member of the serine\/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1\/TAB1 and MAP3K7P2\/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8\/JNK, MAP2K4\/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug \/ Rabbit","offer_id":49476668719384,"sku":"R32443","price":439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_76de846d-079b-4891-ad84-170e618fcd30.jpg?v=1734479164","url":"https:\/\/danabiosci.com\/products\/r32443","provider":"Dana Bioscience","version":"1.0","type":"link"}