{"product_id":"r32292","title":"TRIB2 Antibody","description":"\u003cp\u003eTribbles homolog 2 is a protein that in humans is encoded by the TRIB2 gene. This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C\/EBP alpha (CCAAT\/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug \/ Rabbit","offer_id":49476681105688,"sku":"R32292","price":439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_4a359d97-ce83-4d8f-9e01-cd2a952e7cd8.jpg?v=1734479634","url":"https:\/\/danabiosci.com\/products\/r32292","provider":"Dana Bioscience","version":"1.0","type":"link"}