{"product_id":"r32086","title":"TGFBR2 Antibody \/ TGF beta Receptor II","description":"\u003cp\u003eTGFBR2 (Transforming growth factor, beta receptor II) is a member of the Ser\/Thr protein kinase family and the TGFB receptor subfamily. It is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor\/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan syndrome, Loeys-Deitz aortic aneurysm syndrome, Osler-Weber-Rendu syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different informs have been characterized.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug \/ Rabbit","offer_id":49476711448856,"sku":"R32086","price":439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_6aab7fac-e5d4-4b80-8d47-3928fdb9b0a8.jpg?v=1734480301","url":"https:\/\/danabiosci.com\/products\/r32086","provider":"Dana Bioscience","version":"1.0","type":"link"}