{"product_id":"r31854","title":"Chk2 Antibody \/ CHEK2","description":"\u003cp\u003eChk2 is a serine\/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest, activation of DNA repair and apoptosis in response to the presence of DNA double-strand breaks. May also negatively regulate cell cycle progression during unperturbed cell cycles. Following activation, phosphorylates numerous effectors preferentially at the consensus sequence [L-X-R-X-X-S\/T]. Regulates cell cycle checkpoint arrest through phosphorylation of CDC25A, CDC25B and CDC25C, inhibiting their activity. [UniProt]\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug \/ Rabbit","offer_id":49476728815896,"sku":"R31854","price":439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_0b0d4338-8d0f-4014-9871-c503385678db.jpg?v=1734481042","url":"https:\/\/danabiosci.com\/products\/r31854","provider":"Dana Bioscience","version":"1.0","type":"link"}