{"product_id":"r31677","title":"MFN1 Antibody","description":"\u003cp\u003eMitofusin-1 is a protein that in humans is encoded by the MFN1 gene. It is a mitochondrial member of the dynamin family of molecules. It is ubiquitously expressed, and found in the outer mitochondrial membrane. The protein encoded by this gene is a mediator of mitochondrial fusion, and thereby contribute to the dynamic balance between fusion and fission that determines mitochondria morphology. MFN1 is known to form oligomers, either with itself or MFN­2, and to undergo ubiquitination by MARCH5. It has two key domains; One is a coiled­coil region that mediates MFN­1\/2 binding, and a second is a GTPase domain whose cleavage of GTP is necessary for membrane fusion. Overexpression causes perinuclear mitochondrial clustering.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug \/ Rabbit","offer_id":49476737630488,"sku":"R31677","price":439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_07138161-733f-4db5-bdb6-f04a835327b4.jpg?v=1734481502","url":"https:\/\/danabiosci.com\/products\/r31677","provider":"Dana Bioscience","version":"1.0","type":"link"}