{"product_id":"r31656","title":"RACK1 Antibody","description":"Guanine nucleotide-binding protein subunit beta-2-like 1, also known as RACK1, is a 35kDa protein that in humans is encoded by the GNB2L1 gene. It is mapped to 5q35.3. It is a major component of translating ribosomes, which harbor significant amounts of PKC. This gene can provide a physical and functional link between \u003ca href=\"..\/search_result.php?search_txt=pkc\"\u003ePKC\u003c\/a\u003e signaling and ribosome activation. GNB2L1\/RACK1 is also a mediator of agonist-induced Ca(2+) release. Additionally, it is an essential component of an oxygen-independent mechanism for regulating \u003ca href=\"..\/search_result.php?search_txt=hif1a\"\u003eHIF1A\u003c\/a\u003e stability. Overexpression of RACK1 and PKC-alpha suppressed \u003ca href=\"..\/search_result.php?search_txt=clock\"\u003eCLOCK\u003c\/a\u003e-BMAL1 transcriptional activity, and it stimulated phosphorylation of BMAL1 by PKC-alpha in vitro.","brand":"NSJ Bioreagents","offers":[{"title":"100 ug \/ Rabbit","offer_id":49476738547992,"sku":"R31656","price":439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_1377bf3b-74df-4485-beaa-4be105236a26.jpg?v=1734481566","url":"https:\/\/danabiosci.com\/products\/r31656","provider":"Dana Bioscience","version":"1.0","type":"link"}