{"product_id":"r31636","title":"IRS1 Antibody","description":"\u003cp\u003eInsulin receptor substrate 1 is a signalling adapter protein that in humans is encoded by the IRS1 gene. It is mapped to 2q36.3. This gene exhibited no intrinsic enzyme activity, and it can serve as a docking protein involved in binding and activating other signal transduction molecules after being phosphorylated on tyrosine by insulin receptor kinase. IRS1 plays a key role in transmitting signals from the insulin and insulin-like growth factor-1(IGF-1) receptors to intracellular pathways PI3K\/Akt and Erk MAP kinase pathways. IRS1 also has important biological function for both metabolic and mitogenic(growth promoting) pathways. In addition to those, it is a key regulator of PI3K within malignant cells.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug \/ Rabbit","offer_id":49476739268888,"sku":"R31636","price":439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_053b730c-f33a-4ba3-aa56-40134fccf5bd.jpg?v=1734481613","url":"https:\/\/danabiosci.com\/products\/r31636","provider":"Dana Bioscience","version":"1.0","type":"link"}