{"product_id":"r31605","title":"Estrogen Receptor Antibody (alpha)","description":"Estrogen receptor alpha (ER\u003cfont face=\"symbol\"\u003ea\u003c\/font\u003e), also known as NR3A1, is one of two main types of estrogen receptor, a nuclear protein that is activated by the sex hormone estrogen. ERs are involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. In humans, ER\u003cfont face=\"symbol\"\u003ea\u003c\/font\u003e is encoded by the gene ESR1. It is mapped to 6q25.1. This gene is a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2\/beta. Estrogen and its receptors are essential for sexual development and reproductive function, it also play a role in other tissues such as bone.","brand":"NSJ Bioreagents","offers":[{"title":"100 ug \/ Rabbit","offer_id":49476740841752,"sku":"R31605","price":439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_7d1d95fd-7474-4e8f-9919-9c315aad9104.jpg?v=1734481694","url":"https:\/\/danabiosci.com\/products\/r31605","provider":"Dana Bioscience","version":"1.0","type":"link"}