{"product_id":"r31588","title":"C\/EBP beta Antibody","description":"CCAAT\/enhancer-binding protein beta, also known as is C\/EBP beta, is a protein that in humans is encoded by the CEBPB gene. The protein encoded by this intronless gene is a bZIP transcription factor that can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the\u003ca href=\"..\/search_result.php?search_txt=il-6\"\u003eIL-6\u003c\/a\u003egene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. C\/EBP beta is critical for normal macrophage functioning, an important immune cell sub-type. Observational work has shown that expression of C\/EBP beta in blood leukocytes is positively associated with muscle strength in humans, emphasizing the importance of the immune system, and particularly macrophages, in the maintenance of muscle function.","brand":"NSJ Bioreagents","offers":[{"title":"100 ug \/ Rabbit","offer_id":49476741660952,"sku":"R31588","price":439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_6890ea87-51f7-4f94-9aac-ca3b4ee68c86.jpg?v=1734481745","url":"https:\/\/danabiosci.com\/products\/r31588","provider":"Dana Bioscience","version":"1.0","type":"link"}