{"product_id":"r31426","title":"MUC1 Antibody","description":"\u003cp\u003eMucin 1 protein is encoded by the MUC1 gene in humans. This gene encodes a membrane-bound protein that is a member of the mucin family. Family members are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. MUC1 is a transmembrane protein normally expressed on the apical borders of secretory epithelial cells. Overexpression is often associated with colon, breast, ovarian, lung and pancreatic cancers. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. It stimulated ESR1-mediated transcription and contributed to estradiol-mediated growth and survival of breast cancer cells. This protein also can suppress pulmonary innate immunity, and its anti-inflammatory activity may play an important modulatory role during microbial infection.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug \/ Rabbit","offer_id":49476749590808,"sku":"R31426","price":439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_0eb89fc4-b016-4437-bc03-9555051999a2.jpg?v=1734482199","url":"https:\/\/danabiosci.com\/products\/r31426","provider":"Dana Bioscience","version":"1.0","type":"link"}