{"product_id":"r31346","title":"FAT10 Antibody","description":"\u003cp\u003eUbiquitin D, Diubiquitin or FAT10 (HLA-F-adjacent transcript 10), is a protein that in humans is encoded by the UBD gene. It is a ubiquitin-like protein modifier that can be covalently attached to target protein and subsequently leads to their degradation by the 26S proteasome in a NUB1L-dependent manner. This gene may be involved in dendritic cell (DC) maturation, the process by which immature dendritic cells differentiate into fully competent antigen-presenting cells that initiate T-cell responses. It may be involved in the formation of aggresomes when proteasome is saturated or impaired. FAT10 mediates apoptosis in a caspase-dependent manner, especially in renal epithelium and tubular cells during renal diseases such as polycystic kidney disease and Human immunodeficiency virus (HIV)-associated nephropathy (HIVAN). It may also function as a survival factor.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug \/ Rabbit","offer_id":49476753391896,"sku":"R31346","price":439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_eb414674-b5ba-4333-8e91-ed1dc61a58d3.jpg?v=1734482346","url":"https:\/\/danabiosci.com\/products\/r31346","provider":"Dana Bioscience","version":"1.0","type":"link"}