{"product_id":"r31301","title":"HDAC5 Antibody","description":"\u003cp\u003eHistone deacetylase 5 is an enzyme that in humans is encodes by the HDAC5 gene. The protein encoded by this gene belongs to the class II histone deacetylase\/acuc\/apha family. This gene is mapped to 17q21.31. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation\/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC5 possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2(MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is though to be associated with colon cancer.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug \/ Rabbit","offer_id":49476755521816,"sku":"R31301","price":439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_6fa42b03-d9f6-4fe4-8294-6482eb285e26.jpg?v=1734482444","url":"https:\/\/danabiosci.com\/products\/r31301","provider":"Dana Bioscience","version":"1.0","type":"link"}