{"product_id":"r31275","title":"Beta Arrestin 1 Antibody","description":"\u003cp\u003eBeta Arrestin 1 is a protein which in humans is encoded by the ARRB1 gene. Members of arrestin\/beta-arrestin protein family are though to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. By fluorescence in situ hybridization,this gene is mapped to 11q13.4. Beta Arrestin 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK\/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug \/ Rabbit","offer_id":49476756570392,"sku":"R31275","price":439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_0c501206-122a-40c2-b893-987979773106.jpg?v=1734482511","url":"https:\/\/danabiosci.com\/products\/r31275","provider":"Dana Bioscience","version":"1.0","type":"link"}