{"product_id":"r30811","title":"GAT-1 Antibody","description":"\u003cp\u003eSLC6A1 (Solute Carrier family 6(Neurotransmitter transporter, Gaba), Member 1), also called GABATR, GABATHG and GAT-1, encodes a gamma-aminobutyric acid (GABA) transporter, which removes GABA from the synaptic cleft. Zomot et al.(2007) showed that introduction of a negatively charged amino acid at or near one of the two putative sodium binding sites of GAT-1 from rat brain renders both net flux and exchange of GABA largely chloride independent. By in vitro functional expression studies, the GAT-1 insertion promoter (two copies of the sequence) had significantly greater promoter activity than the noninsertion (one copy of the sequence) promoter, which in turn had greater activity than a promoterless control. Studies of postmortem hippocampus from 69 African American individuals showed that overall expression decreased with age.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug \/ Rabbit","offer_id":49476801331480,"sku":"R30811","price":439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_0d860a00-519b-4b3b-94d3-ee35cbb07a03.jpg?v=1734483596","url":"https:\/\/danabiosci.com\/products\/r30811","provider":"Dana Bioscience","version":"1.0","type":"link"}