{"product_id":"r30746","title":"NDUFA1 Antibody","description":"\u003cp\u003eNADH-ubiquinone oxidoreductase 1 alpha subcomplex 1 is a subunit of mitochondrial NADH: ubiquinone oxidoreductase, also known as mitochondrial complex I. The NDUFA1 gene is mapped to chromosome Xq24. The deduced polypeptide sequence of NDUFA1 was found to have an N-terminal hydrophobic domain, likely to be a transmembrane domain, and a C-terminal hydrophilic domain. And the gene contains 3 exons and spans about 5.0 kb of genomic DNA. Complementation with hamster Ndufa1 cDNA restored the rotenone-sensitive complex I activity of these mutant cells to approximately 100% of the parent cell activity. The findings established that the protein is absolutely essential for an active complex I in mammals. The protein is one of about 31 components of the hydrophobic protein(HP) fraction of complex I which is involved in proton translocation.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug \/ Rabbit","offer_id":49476815814936,"sku":"R30746","price":439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_36f12bd0-1714-4bb9-acdf-0101dcf46d67.jpg?v=1734483740","url":"https:\/\/danabiosci.com\/products\/r30746","provider":"Dana Bioscience","version":"1.0","type":"link"}