{"product_id":"r30585","title":"XIAP Antibody","description":"\u003cp\u003eBIRC4, baculoviral IAP repeat-containing protein 4 is also known as X-linked inhibitor of apoptosis protein, or XIAP. The BIRC4 gene comprises 6 exons. This gene is mapped to chromosome Xq25. This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. XIAP functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug \/ Rabbit","offer_id":49476823843096,"sku":"R30585","price":439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_59c2daab-b3ea-4301-8ba1-b54441fcee4d.jpg?v=1734484106","url":"https:\/\/danabiosci.com\/products\/r30585","provider":"Dana Bioscience","version":"1.0","type":"link"}