{"product_id":"r30365","title":"Caspase-8 Antibody","description":"\u003cp\u003eMost upstream protease of the activation cascade of caspases responsible for the TNFRSF6\/FAS mediated and TNFRSF1A induced cell death. Binding to the adapter molecule FADD recruits it to either receptor. The resulting aggregate called death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. The active dimeric enzyme is then liberated from the DISC and free to activate downstream apoptotic proteases including CASP3\/4\/6\/7\/9\/10. [UniProt]\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug \/ Rabbit","offer_id":49476836262168,"sku":"R30365","price":439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_b76aa4e6-877c-421a-9d61-7732367711f8.jpg?v=1734484611","url":"https:\/\/danabiosci.com\/products\/r30365","provider":"Dana Bioscience","version":"1.0","type":"link"}