{"product_id":"r30278","title":"Caspase-2 Antibody","description":"\u003cp\u003eCaspase-2\/CASP2, which is involved in stress-induced apoptosis, is recruited into a large protein complex, the molecular composition of which remains elusive. Activation of Caspase-2 occurs in a complex that contains the death domain-containing protein PIDD, whose expression is induced by p53, and the adaptor protein RAIDD. Increased PIDD expression resulted in spontaneous activation of Caspase-2 and sensitization to apoptosis by genotoxic stimuli. CASP2 acts both as a positive and negative cell death effector, depending upon cell lineage and stage of development.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug \/ Rabbit","offer_id":49476838949144,"sku":"R30278","price":439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_c2199139-2acb-4136-ba26-379ea45af13f.jpg?v=1734484732","url":"https:\/\/danabiosci.com\/products\/r30278","provider":"Dana Bioscience","version":"1.0","type":"link"}