{"product_id":"ppm1d-antibody-abccs45355","title":"PPM1D Antibody","description":"\u003ch4\u003eSize\u003c\/h4\u003e\u003cp\u003e100ul\u003c\/p\u003e\u003ch4\u003eClone Number\u003c\/h4\u003e\u003cp\u003e\u003c\/p\u003e\u003ch4\u003eAliases\u003c\/h4\u003e\u003cp\u003eEC 3.1.3.16 antibody; p53 induced protein phosphatase 1 antibody; p53-induced protein phosphatase 1 antibody; PP2C delta antibody; PP2C-delta antibody; PP2CD antibody; Ppm1d antibody; PPM1D_HUMAN antibody; Protein phosphatase 1D antibody; protein phosphatase 1D magnesium-dependent delta isoform antibody; Protein phosphatase 2C delta isoform antibody; Protein phosphatase 2C isoform delta antibody; Protein phosphatase magnesium dependent 1 delta antibody; Protein phosphatase magnesium-dependent 1 delta antibody; Protein phosphatase Mg2+\/Mn2+ dependent 1D antibody; Protein phosphatase Wip1 antibody; Wild type p53 induced phosphatase 1 antibody; WIP 1 antibody; WIP1 antibody\u003c\/p\u003e\u003ch4\u003eImmunogen Species\u003c\/h4\u003e\u003cp\u003eHomo sapiens (Human)\u003c\/p\u003e\u003ch4\u003eUniProt ID\u003c\/h4\u003e\u003cp\u003eO15297\u003c\/p\u003e\u003ch4\u003eImmunogen\u003c\/h4\u003e\u003cp\u003eRecombinant Human Protein phosphatase 1D protein (1-250AA)\u003c\/p\u003e\u003ch4\u003eRaised in\u003c\/h4\u003e\u003cp\u003eRabbit\u003c\/p\u003e\u003ch4\u003eSpecies Reactivity\u003c\/h4\u003e\u003cp\u003eHuman, Rat\u003c\/p\u003e\u003ch4\u003eTested Applications\u003c\/h4\u003e\u003cp\u003eELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200\u003c\/p\u003e\u003ch4\u003eBackground\u003c\/h4\u003e\u003cp\u003eRequired for the relief of p53-dependent checkpoint mediated cell cycle arrest. Binds to and dephosphorylates \\\\\\'Ser-15\\\\\\' of TP53 and \\\\\\'Ser-345\\\\\\' of CHEK1 which contributes to the functional inactivation of these proteins. Mediates MAPK14 dephosphorylation and inactivation (PubMed:21283629).\u003c\/p\u003e\u003ch4\u003eClonality\u003c\/h4\u003e\u003cp\u003ePolyclonal\u003c\/p\u003e\u003ch4\u003eIsotype\u003c\/h4\u003e\u003cp\u003eIgG\u003c\/p\u003e\u003ch4\u003ePurification Method\u003c\/h4\u003e\u003cp\u003eAntigen Affinity Purified\u003c\/p\u003e\u003ch4\u003eConjugate\u003c\/h4\u003e\u003cp\u003eNon-conjugated\u003c\/p\u003e\u003ch4\u003eBuffer\u003c\/h4\u003e\u003cp\u003ePBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\u003ch4\u003eForm\u003c\/h4\u003e\u003cp\u003eLiquid\u003c\/p\u003e\u003ch4\u003eStroage\u003c\/h4\u003e\u003cp\u003eUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003ch4\u003eTarget Names\u003c\/h4\u003e\u003cp\u003ePPM1D\u003c\/p\u003e\u003ch4\u003eResearch Areas\u003c\/h4\u003e\u003cp\u003eCancer; Signal transduction\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"Default Title","offer_id":42350234501354,"sku":"ABCCS45355","price":299.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_c888f745-9cb8-4b9c-9eb7-727b1aa78214.png?v=1650901088","url":"https:\/\/danabiosci.com\/products\/ppm1d-antibody-abccs45355","provider":"Dana Bioscience","version":"1.0","type":"link"}