{"product_id":"ppig-polyclonal-antibody-abcb14399","title":"PPIG Polyclonal Antibody","description":"\u003ch4\u003eAb type\u003c\/h4\u003e\u003cp\u003ePrimary antibody\u003c\/p\u003e\u003ch4\u003eBackground\u003c\/h4\u003e\u003cp\u003eCatalytic activity:Peptidylproline (omega=180) = peptidylproline (omega=0).,The RS domain is required for the interaction with the phosphorylated C-terminal domain of RNA polymerase II.,enzyme regulation:Cyclosporin A (CsA)-sensitive.,PPIases accelerate the folding of proteins.,PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.,PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be implicated in the folding, transport, and assembly of proteins. May play an important role in the regulation of pre-mRNA splicing.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,Belongs to the cyclophilin-type PPIase family.,Contains 1 PPIase cyclophilin-type domain.,subcellular location:Colocalizes with RNA splicing factors at nuclear speckles.,subunit:Interacts with CLK1, PNN and with the phosphorylated C-terminal domain of RNA polymerase II.,tissue specificity:Ubiquitous.,\u003c\/p\u003e\u003ch4\u003eReactivity\u003c\/h4\u003e\u003cp\u003eHuman, Rat, Mouse\u003c\/p\u003e\u003ch4\u003eClonality\u003c\/h4\u003e\u003cp\u003ePolyclonal\u003c\/p\u003e\u003ch4\u003eHost\u003c\/h4\u003e\u003cp\u003eRabbit\u003c\/p\u003e\u003ch4\u003eIsotype\u003c\/h4\u003e\u003cp\u003eIgG\u003c\/p\u003e\u003ch4\u003eImmunogen\u003c\/h4\u003e\u003cp\u003eSynthesized peptide derived from human protein . at AA range: 290-370\u003c\/p\u003e\u003ch4\u003eStorage Stability\u003c\/h4\u003e\u003cp\u003e-20°C for 1 year\u003c\/p\u003e\u003ch4\u003eConcentration\u003c\/h4\u003e\u003cp\u003e1 mg\/ml\u003c\/p\u003e\u003ch4\u003eMolecularWeight_Da\u003c\/h4\u003e\u003cp\u003e\u003c\/p\u003e\u003ch4\u003esynonyms\u003c\/h4\u003e\u003cp\u003ePeptidyl-prolyl cis-trans isomerase G ;PPIase G;Peptidyl-prolyl isomerase G;EC 5.2.1.8;CASP10;Clk-associating RS-cyclophilin;CARS-Cyp;CARS-cyclophilin;SR-cyclophilin;SR-cyp;SRcyp;C\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":42405119688938,"sku":"ABCB14399","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_29cb1dde-5887-4726-ab3e-d01c71778926.png?v=1645234455","url":"https:\/\/danabiosci.com\/products\/ppig-polyclonal-antibody-abcb14399","provider":"Dana Bioscience","version":"1.0","type":"link"}