{"product_id":"pkc-zeta-phospho-thr560-polyclonal-antibody-abcb07020","title":"PKC Zeta (Phospho Thr560) Polyclonal Antibody","description":"\u003ch4\u003eAb type\u003c\/h4\u003e\u003cp\u003ePrimary antibody\u003c\/p\u003e\u003ch4\u003eBackground\u003c\/h4\u003e\u003cp\u003eProtein kinase C (PKC) zeta is a member of the PKC family of serine\/threonine kinases which are involved in a variety of cellular processes such as proliferation| differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent| PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore| it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes| it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to| but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms. \u003c\/p\u003e\u003ch4\u003eReactivity\u003c\/h4\u003e\u003cp\u003eHuman, Mouse, Rat, Monkey\u003c\/p\u003e\u003ch4\u003eClonality\u003c\/h4\u003e\u003cp\u003ePolyclonal\u003c\/p\u003e\u003ch4\u003eHost\u003c\/h4\u003e\u003cp\u003eRabbit\u003c\/p\u003e\u003ch4\u003eIsotype\u003c\/h4\u003e\u003cp\u003eIgG\u003c\/p\u003e\u003ch4\u003eImmunogen\u003c\/h4\u003e\u003cp\u003eThe antiserum was produced against synthesized peptide derived from human PKC zeta around the phosphorylation site of Thr560. AA range:526-575\u003c\/p\u003e\u003ch4\u003eStorage Stability\u003c\/h4\u003e\u003cp\u003e-20°C for 1 year\u003c\/p\u003e\u003ch4\u003eConcentration\u003c\/h4\u003e\u003cp\u003e1 mg\/ml\u003c\/p\u003e\u003ch4\u003eMolecularWeight_Da\u003c\/h4\u003e\u003cp\u003e67660\u003c\/p\u003e\u003ch4\u003esynonyms\u003c\/h4\u003e\u003cp\u003eProtein kinase C zeta type; PRKCZ; PKC2; Protein kinase C zeta type; nPKC-zeta\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":42404507058410,"sku":"ABCB07020","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_353fd5af-94a8-46f3-baef-46f9ae909d16.png?v=1645222779","url":"https:\/\/danabiosci.com\/products\/pkc-zeta-phospho-thr560-polyclonal-antibody-abcb07020","provider":"Dana Bioscience","version":"1.0","type":"link"}