{"product_id":"pcbp2-antibody-abccs57092","title":"PCBP2 Antibody","description":"\u003ch4\u003eSize\u003c\/h4\u003e\u003cp\u003e100ug\u003c\/p\u003e\u003ch4\u003eClone Number\u003c\/h4\u003e\u003cp\u003e\u003c\/p\u003e\u003ch4\u003eAliases\u003c\/h4\u003e\u003cp\u003eAlpha CP2 antibody; Alpha-CP2 antibody; alphaCP-2 antibody; Cbp antibody; CTBP antibody; Heterogeneous nuclear ribonucleoprotein E2 antibody; Heterogenous nuclear ribonucleoprotein E2 antibody; hnRNP E2 antibody; hnRNP-E2 antibody; HNRNPE2 antibody; Hnrnpx antibody; HNRPE2 antibody; Hnrpx antibody; MGC110998 antibody; PCBP2 antibody; PCBP2_HUMAN antibody; poly(rC) binding protein 2 antibody; Poly(rC)-binding protein 2 antibody; Putative heterogeneous nuclear ribonucleoprotein X antibody; rCbinding protein 2 antibody\u003c\/p\u003e\u003ch4\u003eImmunogen Species\u003c\/h4\u003e\u003cp\u003eHomo sapiens (Human)\u003c\/p\u003e\u003ch4\u003eUniProt ID\u003c\/h4\u003e\u003cp\u003eQ15366\u003c\/p\u003e\u003ch4\u003eImmunogen\u003c\/h4\u003e\u003cp\u003eRecombinant Human Poly(rC)-binding protein 2 protein (171-293AA)\u003c\/p\u003e\u003ch4\u003eRaised in\u003c\/h4\u003e\u003cp\u003eRabbit\u003c\/p\u003e\u003ch4\u003eSpecies Reactivity\u003c\/h4\u003e\u003cp\u003eHuman\u003c\/p\u003e\u003ch4\u003eTested Applications\u003c\/h4\u003e\u003cp\u003eELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500\u003c\/p\u003e\u003ch4\u003eBackground\u003c\/h4\u003e\u003cp\u003eSingle-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly(rC)-binding protein. Binds also poly(rU). Negatively regulates cellular antiviral responses mediated by MAVS signaling (PubMed:19881509). It acts as an adapter between MAVS and the E3 ubiquitin ligase ITCH, therefore triggering MAVS ubiquitination and degradation (PubMed:19881509).\u003c\/p\u003e\u003ch4\u003eClonality\u003c\/h4\u003e\u003cp\u003ePolyclonal\u003c\/p\u003e\u003ch4\u003eIsotype\u003c\/h4\u003e\u003cp\u003eIgG\u003c\/p\u003e\u003ch4\u003ePurification Method\u003c\/h4\u003e\u003cp\u003e\u0026gt;95%, Protein G purified\u003c\/p\u003e\u003ch4\u003eConjugate\u003c\/h4\u003e\u003cp\u003eNon-conjugated\u003c\/p\u003e\u003ch4\u003eBuffer\u003c\/h4\u003e\u003cp\u003ePreservative: 0.03% Proclin 300\u003cbr\u003eConstituents: 50% Glycerol, 0.01M PBS, pH 7.4\u003c\/p\u003e\u003ch4\u003eForm\u003c\/h4\u003e\u003cp\u003eLiquid\u003c\/p\u003e\u003ch4\u003eStroage\u003c\/h4\u003e\u003cp\u003eUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003ch4\u003eTarget Names\u003c\/h4\u003e\u003cp\u003ePCBP2\u003c\/p\u003e\u003ch4\u003eResearch Areas\u003c\/h4\u003e\u003cp\u003eEpigenetics and Nuclear Signaling; Microbiology\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"Default Title","offer_id":42285468844266,"sku":"ABCCS57092","price":299.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_9a4ae1d8-1e5c-45fa-939e-54acb587e806.png?v=1650884338","url":"https:\/\/danabiosci.com\/products\/pcbp2-antibody-abccs57092","provider":"Dana Bioscience","version":"1.0","type":"link"}