NSJ Bioreagents
SKU:V9265SAF-100UG
Recombiant Ki-67 Antibody, 100 ug
Recombiant Ki-67 Antibody, 100 ug
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Ki-67 antigen is a nuclear, non-histone protein that is present in all stages of the cell cycle except G0. This characteristic makes Ki-67 an excellent marker for proliferating cells and is commonly used as one of the prognostic factors in cancer studies. A correlation has been demonstrated between Ki-67 index and the histo-pathological grade of neoplasms. Assessment of Ki-67 expression in renal and ureter tumors shows a correlation between tumor proliferation and disease progression, thus making it possible to differentiate high-risk patients. Ki-67 expression may also prove to be important for distinguishing between malignant and benign peripheral nerve sheath tumors. Ki-67 labeling index has been shown to be a prognostic marker in a number of neoplasms including grade II astrocytoma, oligodendroglioma, colon carcinoma, and breast carcinoma. In general, Ki-67 is a good marker of proliferating cell populations.
Specifications
| Catalog No | V9265SAF-100UG |
|---|---|
| Family | Primary antibody |
| Qty | 100 ug |
| Formulation | 1 mg/ml in 1X PBS; BSA free, sodium azide free |
| Format | Purified |
| Clone | MKI67/4945R |
| Host Animal | Rabbit |
| Clonality | Recombinant Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Species Reactivity | Human |
| Application | WB, IHC-P |
| Application Details | Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml |
| Application Note | Optimal dilution of the recombinant Ki-67 antibody should be determined by the researcher. |
| Localization | Nuclear |
| Immunogen | A portion of amino acids 2293-2478 from the human protein was used as the immunogen for the recombinant Ki-67 antibody. |
| Purity | Protein A/G affinity |
| Storage | Aliquot the recombinant Ki-67 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This recombinant Ki-67 antibody is available for research use only. |
| Uniprot # | P46013 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/recombiant-ki-67-antibody-mki674945r-v9265 |
| Title | Recombiant Ki-67 Antibody |
| Description | Ki-67 antigen is a nuclear, non-histone protein that is present in all stages of the cell cycle except G0. This characteristic makes Ki-67 an excellent marker for proliferating cells and is commonly used as one of the prognostic factors in cancer studies. A correlation has been demonstrated between Ki-67 index and the histo-pathological grade of neoplasms. Assessment of Ki-67 expression in renal and ureter tumors shows a correlation between tumor proliferation and disease progression, thus making it possible to differentiate high-risk patients. Ki-67 expression may also prove to be important for distinguishing between malignant and benign peripheral nerve sheath tumors. Ki-67 labeling index has been shown to be a prognostic marker in a number of neoplasms including grade II astrocytoma, oligodendroglioma, colon carcinoma, and breast carcinoma. In general, Ki-67 is a good marker of proliferating cell populations. |
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