{"product_id":"nsj-v9186-20ug","title":"C-terminal-binding protein 2 Antibody \/ CTBP2, 20 ug","description":"\u003cp\u003eThe gene CTBP2 (C-terminal binding protein 2) encodes a member of the CtBP-family. The gene is mapped to human chromosome 21q21.3. It is found to be expressed ubiquitously, with higher expression in the heart, skeletal muscle, and pancreas. The gene CTBP2 (C-terminal binding protein 2) encodes a protein that functions as a transcriptional co-repressor of several tumor suppressor genes resulting in enhanced cancer cell migration and invasion. Its expression is found to be upregulated in hepatocellular carcinoma (HCC). It may be a potential prognostic marker for post liver resection HCC. It is involved in several types of tumor initiation, progression and response to therapy. It is found to interact with the C-terminal region of adenovirus type 2\/5 E1A protein, a region that negatively regulates tumorigenicity and the extent of oncogenic transformation.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"20 ug","offer_id":51547908735256,"sku":"V9186-20UG","price":259.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_ff04990d-f6f1-489d-ac42-e8822c0646c0.jpg?v=1768268408","url":"https:\/\/danabiosci.com\/products\/nsj-v9186-20ug","provider":"Dana Bioscience","version":"1.0","type":"link"}