{"product_id":"nsj-v8652-20ug","title":"Recombinant Cyclin D1 Antibody, 20 ug","description":"\u003cp\u003eRecognizes a protein of 36kDa, identified as cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL\/SLL and follicular lymphomas (cyclin D1 negative). Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"20 ug","offer_id":51548003008792,"sku":"V8652-20UG","price":259.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_55afdae5-a5ae-4cd3-8492-d39ca7cf87cf.jpg?v=1768270865","url":"https:\/\/danabiosci.com\/products\/nsj-v8652-20ug","provider":"Dana Bioscience","version":"1.0","type":"link"}