{"product_id":"nsj-v8512-20ug","title":"CD25 Antibody \/ IL2RA, 20 ug","description":"\u003cp\u003eRecognizes a protein of 55kDa, identified as CD25 (Workshop IV; Code A27). CD25 is expressed on activated T- and B-cells and activated monocytes\/macrophages. With respect to lymphomas, CD25 is present on malignant cells of Hodgkins disease, HTLV-1+ adult T-cell leukemia, cutaneous T-cell lymphoma, and hair cell leukemia. Increased levels of soluble CD25 are observed in the leukemias\/lymphomas and inflammatory\/ autoimmune diseases. CD25 molecule alone appears to function as a low affinity receptor and associates with CD122 (IL-2R chain, p75) and CD132 (common chain) to form the high affinity IL-2 receptor complex. CD25 antibodies detect three epitope regions, A, B and C. This MAb recognizes the epitope B, which is located at residue 3-104 of CD25 and can effectively block IL-2 binding to CD25.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"20 ug","offer_id":51548018376984,"sku":"V8512-20UG","price":259.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_acf36f5d-082e-4b03-a83a-f112d875bf19.jpg?v=1768271376","url":"https:\/\/danabiosci.com\/products\/nsj-v8512-20ug","provider":"Dana Bioscience","version":"1.0","type":"link"}