{"product_id":"nsj-v8347-100ug","title":"PD1 Antibody \/ PDCD1, 100 ug","description":"\u003cp\u003ePD-1 is expressed on a subset of CD4-CD8-thymocytes, and on activated T and B cells. PD-1 is thought to be involved in lymphocyte clonal selection and peripheral tolerance. The PD-1 ligands, PD-L1 (also known as B7-H1) and PD-L2 (B7-DC), are members of the B7 immunoglobulin superfamily. PD-1 is transiently expressed on CD4 and CD8 thymocytes as well as activated T and B-lymphocytes and myeloid cells. Additionally, Pdcd1 mRNA is expressed in developing B-lymphocytes during the pro-B-cell stage. \u003cstrong\u003eThe RMP1-14 antibody has been reported to block the binding of PD-1 to its ligands (B7-H1 and B7-DC) and to inhibit T cell proliferation and cytokine production co-stimulated by macrophages (but not by dendritic cells and B cells).\u003c\/strong\u003e\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51548038955288,"sku":"V8347-100UG","price":559.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_77cd3819-74cf-40d8-8237-b937567477e7.jpg?v=1768272023","url":"https:\/\/danabiosci.com\/products\/nsj-v8347-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}