{"product_id":"nsj-v8188-20ug","title":"Actinin Alpha 2 Antibody \/ Sarcomeric Alpha Actinin \/ ACTN2, 20 ug","description":"\u003cp\u003eAlpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In non-muscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"20 ug","offer_id":51548057469208,"sku":"V8188-20UG","price":259.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_428b2a55-1a7c-4ba7-be1c-d7e5f278d0b5.jpg?v=1768272619","url":"https:\/\/danabiosci.com\/products\/nsj-v8188-20ug","provider":"Dana Bioscience","version":"1.0","type":"link"}