{"product_id":"nsj-v8107-100ug","title":"TAL1 Antibody \/ T-cell acute lymphocytic leukemia protein 1, 100 ug","description":"\u003cp\u003eActivation of TAL1 characterizes up to 60% of cases of human T cell acute lymphoblastic leukemia, making it the most frequent gain-of-function mutation observed in this disorder. TAL1 (also designated SCL) is a serine phosphoprotein and basic helix-loop-helix transcription factor known to regulate embryonic hematopoiesis. This transcription factor binds as a heterodimer with E2A and HEB\/HTF4 to a nucleotide sequence motif termed the E-box. In addition, leukemogenesis is accelerated dramatically by transgenic co-expression of TAL1 and the catalytic subunit of casein kinase IIHLH transcription factors.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51548066644248,"sku":"V8107-100UG","price":559.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_7aa8854b-fc76-42a9-a356-9fc6864d0b3a.jpg?v=1768272950","url":"https:\/\/danabiosci.com\/products\/nsj-v8107-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}