{"product_id":"nsj-v7561ihc-7ml","title":"Dystrophin Antibody \/ DMD, 7 ml","description":"\u003cp\u003eDystrophin-glycoprotein complex (DGC) connects the F-Actin cytoskeleton on the inner surface of muscle fibers to the surrounding extracellular matrix, through the cell membrane interface. A deficiency in this protein contributes to Duchenne (DMD) and Becker (BMD) muscular dystrophies. The human dystrophin gene measures 2.4 megabases, has more than 80 exons, produces a 14 kb mRNA and contains at least 8 independent tissue-specific promoters and 2 poly A sites. The dystrophin mRNA can undergo differential splicing and produce a range of transcripts that encode a large set of proteins. Dystrophin represents approximately 0.002% of total striated muscle protein and localizes to triadic junctions in skeletal muscle, where it is thought to influence calcium ion homeostasis and force transmission.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"7 ml","offer_id":51548188213528,"sku":"V7561IHC-7ML","price":559.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_3abee3a4-da2a-4fc2-9230-508c552e5336.jpg?v=1768275199","url":"https:\/\/danabiosci.com\/products\/nsj-v7561ihc-7ml","provider":"Dana Bioscience","version":"1.0","type":"link"}