{"product_id":"nsj-v7488-20ug","title":"NME2 Antibody \/ NM23-H2, 20 ug","description":"\u003cp\u003eThe nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP). In humans, NDP kinases A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and H2, respectively. nm23-H2 is identical in sequence to PuF, a transcription factor that binds to nuclease hypersensitive elements at positions 142 to 115 of the human c-Myc promotor.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"20 ug","offer_id":51548218097944,"sku":"V7488-20UG","price":259.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_04a7d7e7-e93b-4fae-9643-73d46b22c1eb.jpg?v=1768275584","url":"https:\/\/danabiosci.com\/products\/nsj-v7488-20ug","provider":"Dana Bioscience","version":"1.0","type":"link"}