{"product_id":"nsj-v5657-20ug","title":"Cofilin 2 Antibody \/ CFL2, 20 ug","description":"\u003cp\u003eCofilin is ubiquitously expressed in eukaryotic cells where it binds to Actin, thereby regulating the rapid cycling of Actin assembly and disassembly essential for cellular viability. Cofilin is a low molecular weight protein that binds to filamentous (F) Actin by bridging two longitudinally associated Actin subunits changing the F-Actin filament twist. This process is allowed by the dephosphorylation of Cofilin Ser-3 by factors such as opsonized zymosan. Lim kinase 1, a serine kinase, phosphorylates Cofilin and renders it unable to bind and depolymerise F-Actin.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"20 ug","offer_id":51548361883928,"sku":"V5657-20UG","price":259.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_078bd095-4f58-41c0-ae07-31350370b356.jpg?v=1768278855","url":"https:\/\/danabiosci.com\/products\/nsj-v5657-20ug","provider":"Dana Bioscience","version":"1.0","type":"link"}