{"product_id":"nsj-v5592-20ug","title":"CD161 Antibody \/ KLRB1, 20 ug","description":"\u003cp\u003eNatural killer (NK) and T cells express a superfamily of proteins with structural features of C-type lectins. T cells bearing natural killer receptors (NKRs) such as CD94 and CD161 are present in psoriasis. CD161 mediates NK cell activation and functions as an activating receptor. CD161 is a prototypic marker of NK cells, although it is also found on a subset of CD8+ T cells. The expression of NK receptors on CD8+ T cells can be considered a marker of cytotoxic effector T cells that are expanded in vivo after antigenic activation leading to extensive proliferation. The transcription, mRNA accumulation, and surface expression of CD161, a molecule involved in triggering cytotoxicity, is specifically upregulated by IL-12.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"20 ug","offer_id":51548372271384,"sku":"V5592-20UG","price":259.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_73ee42ae-e9f3-4225-b5b1-342e71948069.jpg?v=1768279172","url":"https:\/\/danabiosci.com\/products\/nsj-v5592-20ug","provider":"Dana Bioscience","version":"1.0","type":"link"}