{"product_id":"nsj-v5121-20ug","title":"CDC5L Antibody \/ Cell division cycle 5-like protein, 20 ug","description":"\u003cp\u003eCdc5L (cell division cycle 5-like protein, pombe Cdc5-related protein) is a DNA-binding protein encoded by the human gene CDC5L. Cdc5L contains two HTH Myb-type DNA-binding domains and may shuttle between cytoplasm and nucleus. It is involved in cell cycle control and may act as a transcription activator. Cdc5L is a spliceosomal protein that is highly conserved across species. It belongs to the group of proteins that comprise the core of spliceosomal complexes and are essential for pre-mRNA splicing. Cdc5L is involved in the second catalytic step of pre-mRNA splicing, which involves cleavage at the 3' splice site and the ligation of the exons. This process releases the intact intron lariat. A chromosomal aberration involving Cdc5L is found in multicystic renal dysplasia. This aberration is caused by a translocation (t 6;19,p21;q13.1) with USF-2.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"20 ug","offer_id":51548448751896,"sku":"V5121-20UG","price":259.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_a07fdebf-9b8d-40e5-bf40-1800d029eebf.jpg?v=1768281458","url":"https:\/\/danabiosci.com\/products\/nsj-v5121-20ug","provider":"Dana Bioscience","version":"1.0","type":"link"}