{"product_id":"nsj-v4956-20ug","title":"PAX3 Antibody \/ Paired box 3, 20 ug","description":"\u003cp\u003ePax genes contain paired domains that share strong homology to genes in Drosophila which are involved in programming early development. The product of the PAX3 gene is a DNA-binding protein expressed during early neurogenesis. Pax-3 is a protein containing both a paired domain and a paired-type homeodomain. During early neurogenesis, Pax-3 expression is limited to mitotic cells in the ventricular zone of the developing spinal cord and to distinct regions in the hindbrain, midbrain and diencephalon. In 10-12 day embryos, expression of Pax-3 is also seen in neural crest cells of the developing spinal ganglia, the craniofacial mesectoderm and in limb mesenchyme. Mutations in the MITF and Pax-3 genes, encoding transcription factors, are responsible for Waardenburg syndrome II (WSII) and WSI\/WSIII, respectively.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"20 ug","offer_id":51548544925976,"sku":"V4956-20UG","price":259.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_432e401f-542e-49c6-9ee0-3cd317d433ca.jpg?v=1768282215","url":"https:\/\/danabiosci.com\/products\/nsj-v4956-20ug","provider":"Dana Bioscience","version":"1.0","type":"link"}