{"product_id":"nsj-v4899-20ug","title":"MYCN Antibody \/ n-Myc, 20 ug","description":"\u003cp\u003eThe v-Myc oncogene, initially identified in the MC29 avian retrovirus, causes myelocytomas, carcinomas, sarcomas and lymphomas, and belongs to a family of oncogenes conserved throughout evolution. In humans, the family consists of five genes: c-Myc, N-Myc, R-Myc, L-Myc and B-Myc. Amplification of the N-Myc gene has been found in human neuroblastomas and cell lines. Its amplification correlates well with the stage of neuroblastoma disease. Immunological studies have shown that the human N-Myc gene encodes a nuclear phosphoprotein that exhibits relatively short (30 min) half life in vivo. The prototype member of the family, c-Myc p67, binds DNA in a sequence-specific manner subsequent to dimerization with a second basic region helix-loop-helix leucine zipper motif protein, designated Max.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"20 ug","offer_id":51548553249048,"sku":"V4899-20UG","price":259.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_0704d982-5056-4db3-be14-3fa2f7542e87.jpg?v=1768282457","url":"https:\/\/danabiosci.com\/products\/nsj-v4899-20ug","provider":"Dana Bioscience","version":"1.0","type":"link"}