{"product_id":"nsj-v4865-20ug","title":"Beta-Parvin Antibody \/ PARVB, 20 ug","description":"\u003cp\u003eBeta-parvin, also known as affixin, is a focal adhesion protein belonging to a family of ILKbinding proteins that contain tandem calponin homolog domains. Along with Alpha-parvin, Beta-parvin is one of the most widely researched and characterized members of this family. These two proteins interact with the ILK kinase domain in a way that is mutually exclusive and regulates both the activity of the kinase and actin cytoskeleton adhesion. Studies have shown Beta-parvin to be downregulated within human breast cancer cells, and that its expression may influence the progression of breast cancer (Johnstone, 2008). Additional research indicates a critical role for Beta-parvin in the regulation of cardiac contractility when it is in complex with ILK (Hannigan, 2007).\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"20 ug","offer_id":51548562391320,"sku":"V4865-20UG","price":259.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_6f5b2d7a-8933-46b4-8dde-8d3629951a35.jpg?v=1768282607","url":"https:\/\/danabiosci.com\/products\/nsj-v4865-20ug","provider":"Dana Bioscience","version":"1.0","type":"link"}