{"product_id":"nsj-v4496-20ug","title":"Topo IIa Antibody \/ Topoisomerase II alpha, 20 ug","description":"\u003cp\u003eThe topoisomerase II-Alpha isoform is a 170kDa nuclear protein and plays an important role in DNA synthesis and RNA transcription, as well as chromosomal segregation during mitosis. Topoisomerase II-Alpha is reported to be a sensitive and specific marker of late S-, G2- \u0026amp; M-phases in transformed and developmentally regulated normal cells, and has been shown to be over-expressed in many human cancers. Decreased expression of Topoisomerase II-Alpha is the predominant mechanism of resistance to several chemotherapeutic agents.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"20 ug","offer_id":51548611051800,"sku":"V4496-20UG","price":259.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_a6cdcdcd-077e-4860-b094-16f18170a917.jpg?v=1768284257","url":"https:\/\/danabiosci.com\/products\/nsj-v4496-20ug","provider":"Dana Bioscience","version":"1.0","type":"link"}