{"product_id":"nsj-v4425-100ug","title":"B-cell maturation protein Antibody \/ BCMA \/ CD269 \/ TNFRSF17, 100 ug","description":"\u003cp\u003eThe B cell maturation protein (BCMA) is a type I integral membrane protein that belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is expressed as a 184 amino acid peptide that is expressed only in mature B-lymphocytes and is located on the cis part of the Golgi apparatus. BCMA shares significant homology with TACI (transmembrane activator) within the cysteine-rich domain. TACI has been shown to bind CAML, which induces activation of NFAT (nuclear factor of activated T cells). Both BCMA and TACI have been shown to bind APRIL and TALL-1, which stimulate B cell proliferation in conjunction with other B-cell activators. When overexpressed, TALL-1 stimulates the development of systemic lupus erythaematosus (SLE).\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51548622651672,"sku":"V4425-100UG","price":559.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_5079a5c0-0a81-4a87-a03f-e51dc3ed5945.jpg?v=1768284615","url":"https:\/\/danabiosci.com\/products\/nsj-v4425-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}