{"product_id":"nsj-v4354-20ug","title":"SKIP Antibody \/ SNW1 \/ NCoA-62, 20 ug","description":"\u003cp\u003eNuclear receptor coactivator NCOA62\/SNW1 (also called Nuclear Protein SkiP, SKIIP, Ski-interacting protein) is a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also interact with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"20 ug","offer_id":51548633530648,"sku":"V4354-20UG","price":259.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_b2206233-ec2a-4aef-916f-1d770fe0ed49.jpg?v=1768284948","url":"https:\/\/danabiosci.com\/products\/nsj-v4354-20ug","provider":"Dana Bioscience","version":"1.0","type":"link"}