{"product_id":"nsj-v3697-100ug","title":"Recombinant Mucin-1 Antibody \/ Rabbit Monoclonal, 100 ug","description":"\u003cp\u003eThis MAb reacts with MUC1, a large transmembrane glycoprotein expressed on the ductal surface of normal glandular epithelia. It is used as tracer agent in CA15.3 assays. The extracellular domain of MUC1 largely consists of a highly conserved, O-glycosylated 20 amino acids tandem repeat which can occur 30-100 times per molecule depending on the length of the allele involved. In the vast majority of human carcinomas this protein is up-regulated and poorly glycosylated and appears on the cell surface in a non-polarized fashion. The dominant epitope of this MAb involves both amino acids as well as sugar moieties. Its epitope is destroyed by desialylation i.e. treatment with Neuraminidase.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51548846719256,"sku":"V3697-100UG","price":559.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_f72ec38a-9a55-4dbd-9461-eb2d5fa05edb.jpg?v=1768287796","url":"https:\/\/danabiosci.com\/products\/nsj-v3697-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}