{"product_id":"nsj-v3226-100ug","title":"PSGL-1 Antibody \/ CD162, 100 ug","description":"\u003cp\u003eP selectin glycoprotein ligand 1 (PSGL-1), also called CD162 glycoprotein, functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51548992143640,"sku":"V3226-100UG","price":559.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_218b412a-13df-4344-bf3f-c1ae8ae58fe0.jpg?v=1768289892","url":"https:\/\/danabiosci.com\/products\/nsj-v3226-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}