{"product_id":"nsj-v2006pe-100tests","title":"Cyclin D1 Antibody PE Conjugate, 100 Tests","description":"\u003cp\u003eThis antibody recognizes a protein of 36kDa, identified as Cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression. The antibody is useful in identifying mantle cell lymphomas (Cyclin D1 positive) from CLL\/SLL and follicular lymphomas (Cyclin D1 negative). Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 Tests","offer_id":51549531406616,"sku":"V2006PE-100T","price":559.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_856a1ea2-a4c3-4ab8-a1b2-5075ca5f9f84.jpg?v=1768300494","url":"https:\/\/danabiosci.com\/products\/nsj-v2006pe-100tests","provider":"Dana Bioscience","version":"1.0","type":"link"}