{"product_id":"nsj-rz1220-100ug","title":"Zebrafish E-cadherin Antibody \/ Cdh1 \/ Cadherin 1, 100 ug","description":"\u003cp\u003eE cadherin, also known as epithelial cadherin, cadherin 1 and Cdh1, is a calcium dependent cell adhesion protein that plays a key role in maintaining epithelial tissue structure and integrity. In zebrafish, E cadherin is essential for early embryonic development, particularly during processes such as epiboly, gastrulation, and organ formation.\u003c\/p\u003e\u003cp\u003eE cadherin is a transmembrane glycoprotein that mediates homophilic cell to cell adhesion by forming adherens junctions between neighboring epithelial cells. It is a critical component of the cadherin catenin complex, which connects the actin cytoskeleton to the plasma membrane, thereby regulating tissue architecture and cell polarity.\u003c\/p\u003e\u003cp\u003eIn zebrafish embryos, E cadherin is expressed from the earliest stages of development and is especially important for coordinating cell movements and maintaining cohesion during morphogenesis. Loss or disruption of E cadherin function leads to severe defects in cell adhesion, tissue separation, and embryonic patterning.\u003c\/p\u003e\u003cp\u003eBecause of its conserved role in epithelial biology, zebrafish E cadherin is widely used in research focused on developmental biology, cancer metastasis, tissue regeneration, and epithelial to mesenchymal transition. It also serves as a valuable marker for epithelial cell identity and cell junction integrity in various model systems.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51549546643736,"sku":"RZ1220","price":539.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_11f7071d-9a38-45b2-b2d5-315eb912231e.jpg?v=1768300719","url":"https:\/\/danabiosci.com\/products\/nsj-rz1220-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}