{"product_id":"nsj-rq8884-100ul","title":"TAR DNA binding protein 43 Antibody \/ TDP43 \/ TARDBP, 100 ul","description":"\u003cp\u003eTAR DNA binding protein 43 is a DNA\/RNA-binding protein that shuttles between nucleus and cytoplasm to coordinate RNA metabolism. It recognizes UG-rich sequences via 2 RNA recognition motifs and uses a glycine-rich C-terminus to assemble ribonucleoprotein complexes. TAR DNA binding protein 43 regulates alternative splicing, transcript stability, 3' end processing, and mRNA transport, integrating these steps with transcription-coupled RNA handling across diverse cell types.\u003c\/p\u003e\u003cp\u003eIt participates in stress-responsive RNA granule dynamics and controlled phase behavior, linking RNA sorting to protein quality control pathways. Its nuclear enrichment, regulated export, and post-translational modification states offer quantitative readouts for studies of RNA processing, trafficking, and cellular adaptation in defined model systems.\u003c\/p\u003e\u003cp\u003eThe \u003cb\u003eTAR DNA binding protein 43 antibody\u003c\/b\u003e from NSJ Bioreagents enables specific detection of endogenous TDP-43 in applications such as western blot, immunofluorescence, immunohistochemistry, immunoprecipitation, and RNA-protein pulldown workflows. Researchers use the TAR DNA binding protein 43 antibody to measure total protein levels, assess nuclear-cytoplasmic distribution, and evaluate biochemical fractionation or stress-induced relocalization when paired with appropriate complementary reagents. With high specificity and reproducible performance, the TAR DNA binding protein 43 antibody supports rigorous analysis of RNA-binding protein networks and post-transcriptional regulation.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ul","offer_id":51549617881368,"sku":"RQ8884","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_a293e668-96ee-4469-aa4c-77c429536fa4.jpg?v=1768301162","url":"https:\/\/danabiosci.com\/products\/nsj-rq8884-100ul","provider":"Dana Bioscience","version":"1.0","type":"link"}