{"product_id":"nsj-rq8767-100ug","title":"CENP-R Antibody \/ Centromere protein R \/ ITGB3BP, 100 ug","description":"\u003cp\u003eCentromere protein R is a protein that in humans is encoded by the ITGB3BP gene. This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51549640425752,"sku":"RQ8767","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_2387dc6f-b373-4162-a23a-b342f4c9c366.jpg?v=1768301333","url":"https:\/\/danabiosci.com\/products\/nsj-rq8767-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}