{"product_id":"nsj-rq8702-100ul","title":"Phospho-MDM2 Antibody (pS166), 100 ul","description":"\u003cp\u003ePhosphorylated MDM2 is a post-translationally modified form of the MDM2 protein, an E3 ubiquitin ligase that regulates the stability and activity of the tumor suppressor p53. Phosphorylation of MDM2 at specific residues modulates its localization, interaction with binding partners, and overall activity in the p53 pathway. Researchers often use a Phospho-MDM2 antibody to study these regulatory mechanisms.\u003c\/p\u003e\u003cp\u003e Cellular stress signals such as DNA damage or growth factor stimulation can trigger phosphorylation of MDM2, altering its ability to degrade p53 and impacting cell cycle progression, DNA repair, and apoptosis. Employing a Phospho-MDM2 antibody enables detection of these phosphorylation-dependent changes and provides insights into signaling cascades that control cell fate. \u003c\/p\u003e\u003cp\u003e NSJ Bioreagents offers a high-quality Phospho-MDM2 antibody for applications including western blot, immunoprecipitation, and immunofluorescence. Selecting the right Phospho-MDM2 antibody ensures reliable detection of this critical regulatory modification in cancer biology, cell cycle control, and stress response studies.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ul","offer_id":51549643800856,"sku":"RQ8702","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_bfa89c1e-9715-48d2-88a8-8a9c24032575.jpg?v=1768301435","url":"https:\/\/danabiosci.com\/products\/nsj-rq8702-100ul","provider":"Dana Bioscience","version":"1.0","type":"link"}